You can not prepare for and design a responsive, content-focused, mobile-first site the exact same method.
It’s simple to resort to working more to deal with these brand-new obstacles. Do a desktop and mobile-sized wireframe, then turn around and design a desktop and mobile-sized design. You and your designer have more to work with, at least.
At this moment, you get up and understand you’re stuck in a familiar loop of ever-shrinking revenues and ever-increasing deliverables. Utilizing this old procedure to take on brand-new issues does not truly resolve any of them, and it’s going to eliminate you from absence of sleep, make you bad from absence of earnings, or both.
There are some great concepts drifting around handling brand-new procedures. Some wise folks are of the extremely reasonable viewpoint that the only response is to design in the web browser. Other clever folks have actually confessed for the peaceful rest of us that it’s truly, truly difficult to design easily in the web browser– at least with present tools.
Of the emerging brand-new procedure concepts, those that include responsive HTML/CSS models look extremely appealing. There are some guaranteed difficulties with this technique, not the least of which is the time it takes to develop them when the website material is complex.
Presently, we are effectively utilizing a various technique. It tries to enhance design, advancement, and material time, discovering an economical balance of suitable instructions from all disciplines– something that works, lean and utilizes fast, widely-accessible tools.

[From  smashingmagazine.com]
Do a desktop and mobile-sized wireframe, then turn around and design a desktop and mobile-sized design. Some wise folks are of the extremely reasonable viewpoint that the only response is to design in the internet browser. Other clever folks have actually confessed for the peaceful rest of us that it’s truly, actually tough to design easily in the internet browser– at least with present tools.
Of the emerging brand-new procedure concepts, those that include responsive HTML/CSS models look really appealing.